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This study aims at analysing the determinants of contraceptive use in Egypt, with particular reference to the differentials due to the context and to the area of residence. The increasing use of family planning methods seems to be the intermediate determinant which mostly influences the fertility decline in developing countries, and in particular in those countries which are in an advanced phase of demographic transition. Egypt shows a widespread diffusion of fertility regulation, but the differences among social groups are still extremely marked. Moreover countries with a large territorial extension, like Egypt, are characterized by very different geographical realities and even by strong regional heterogeneities. The conceptualisation of the contextual social-economical factors, linked to the cultural norms typical of the communities to which women belong to and to the opportunities that their residential environment may offer, allow us to better understand the determinants of their choices. This theoretical approach implies the need of a statistical model in which, together with the mechanisms regulating individual choices (micro-dimension), the contextual factors (macro-dimension) may represent the interpretative key-stone. To estimate each individual and regional factors’ effect on contraceptive use, a logistic two-level random intercept model is fitted to EDHS 2000 data; in particular, the use of a multilevel analysis is suggested by the two-level data structure: the first level units are the women; the second level units are their residential regions.